Saccadic movement effects on intraocular drug delivery for a wet-AMD clinical case
Vol. 2 No. 2 (2018), ESB ITA
Vol. 2 No. 2 (2018)

Saccadic movement effects on intraocular drug delivery for a wet-AMD clinical case

ESB ITA
https://doi.org/10.35119/maio.v2i2.79
Published 2018-06-18
Marco Ferroni
Department of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano
Matteo Cereda
Department of Biomedical and Clinical Science Luigi Sacco, Sacco Hospital, University of Milan,
Federica Boschetti
Department of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano
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Ferroni M, Cereda M, Boschetti F. Saccadic movement effects on intraocular drug delivery for a wet-AMD clinical case. MAIO [Internet]. 2018 Jun. 18 [cited 2024 Dec. 26];2(2):86-91. Available from: https://www.maio-journal.com/index.php/MAIO/article/view/79
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Keywords

age-related macular degeneration (AMD); computational fluid-dynamics; saccade; vitreous drug delivery

Abstract

Nowadays, intravitreal injections are the gold standard for the treatment of age-related macular degeneration (AMD). The prediction of the transport mechanism for the injected anti vascular endothelial growth factor (anti-VEGF) is needed in order to understand its distribution and consumption after each injection. Thus, this study aims at implementing a full model of vitreous drug delivery. The main novelty of this work is the coupling between an experimental evaluation of the scleral permeability and a numerical analysis of the saccadic dependency of the transport phenomena.

https://doi.org/10.35119/maio.v2i2.79
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References

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