Condensation on intraocular lenses during vitrectomy: effect of perfluorocarbon liquids
Vol. 2 No. 1 (2018), Original Articles
Vol. 2 No. 1 (2018)

Condensation on intraocular lenses during vitrectomy: effect of perfluorocarbon liquids

Original Articles
https://doi.org/10.35119/maio.v2i1.84
Published 2018-03-08
Yann Dacquay
Retina division, Stein Eye Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California
Joseph R. Lee
UCLA Engineering, Mechanical and Aerospace Engineering University of California, Los Angeles, Los Angeles, California
Andrea Govetto
Retina division, Stein Eye Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California
Matthias Elgeti
Department for Chemistry and Biochemistry, Stein Eye Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California
Wayne L Hubbell
Department for Chemistry and Biochemistry, Stein Eye Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California
Pirouz Kavehpour
UCLA Engineering, Mechanical and Aerospace Engineering University of California, Los Angeles, Los Angeles, California
Jean-Pierre Hubschman
Retina division, Stein Eye Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California
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Dacquay Y, Lee JR, Govetto A, Elgeti M, Hubbell WL, Kavehpour P, Hubschman J-P. Condensation on intraocular lenses during vitrectomy: effect of perfluorocarbon liquids. MAIO [Internet]. 2018 Mar. 8 [cited 2025 Jan. 28];2(1):71-80. Available from: https://www.maio-journal.com/index.php/MAIO/article/view/84
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Keywords

acrylic lenses; condensation; fogging; intraocular lenses (IOL); perfluorocarbon (PFO) liquids; polymethylmethacrylate lenses; posterior capsulotomy; silicone lenses

Abstract

Purpose: To evaluate whether perfluorocarbon (PFO) liquids can exacerbate condensation on intraocular lenses (IOL).

Methods: Two separate experiments were carried out. In the first experiment, a two-segment chamber was constructed out of glass and acrylic panels to serve as an in-vitro eye model. The chamber was placed on a non-activated cooling plate with two IOLs of the same material, one in each segment. 2.0 ml of PFO and/or water for the control were placed in the respective receptacle. The cooling plate was then activated to the desired temperatures. Condensation on the lenses was visually assessed via high-definition ultra-zoom camera by trained observers for three temperatures and three IOL materials.

In the second experiment, Fourier transform infrared (FTIR) spectroscopy wasemployed to determine the composition of the droplets forming after condensation.

Results: The presence of PFO liquid in a closed chamber exacerbates the intensity and likelihood of condensation on all intraocular material types. Condensation of PFO on surfaces in the presence of water was confirmed with FTIR spectroscopy by the isolation of specific absorption bands. Furthermore, material type also affects the characteristics of condensation, with silicone lenses inducing the fastest rate and intensity of condensation.

Conclusions: Our study shows that the presence of perfluoro-n-octane is a significant factor in the formation of condensation on the posterior surface of IOLs when performing vitrectomy in a pseudophakic patient with posterior capsulotomy.

 
https://doi.org/10.35119/maio.v2i1.84
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